Association of serum leptin with various biochemical parameters of bone turnover in maintenance hemodialysis patients
Pakistan Journal of Nutrition 5(2): 180-184
Leptin is a small peptide hormone that is mainly but not exclusively produced in adipose tissue. Leptin is cleared principally by the kidney. Serum leptin concentrations and bone mass are directly related. This cross-sectional study was conducted in patients from Iran with end-stage renal disease (ESRD), who were undergoing maintenance haemodialysis Serum calcium, phosphorus, predialysis serum creatinine, blood urea nitrogen, alkaline phosphatase (ALP), intact serum PTH (iPTH) and serum leptin were measured. In this study a significant difference of serum leptin between males and females of diabetic patients was seen.