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Standardization of an experimental murine model of invasive pulmonary aspergillosis



Standardization of an experimental murine model of invasive pulmonary aspergillosis



Antimicrobial Agents and ChemoTherapy 50(10): 3501-3503



Evaluating new therapeutic agents for invasive aspergillosis requires animal models that are reproducible among different laboratories. We therefore evaluated a murine model of aerosol infection in two independent laboratories and found a high level of both intra- and interlaboratory reproducibility of survival, fungal burden over time, and the efficacy of liposomal amphotericin B.

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Accession: 012821445

Download citation: RISBibTeXText

PMID: 17005844

DOI: 10.1128/aac.00787-06


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