Section 13
Chapter 12,895

The lipid transfer proteins (LTP) essentially concentrate in the skin of Rosaceae fruits as cell surface exposed allergens

Borges, J-P.; Jauneau, A.; Brulé, C.; Culerrier, R.; Barre, A.; Didier, A.; Rougé, P.

Plant Physiology and Biochemistry (Paris) 44(10): 535-542


ISSN/ISBN: 0981-9428
PMID: 17064926
DOI: 10.1016/j.plaphy.2006.09.018
Accession: 012894203

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The localization and distribution of non-specific lipid transfer proteins (nsLTP) allergens in the skin and pulp of Rosaceae fruits (apple, peach, apricot, plum) has been investigated. nsLTP essentially concentrate in the pericarp of the fruits whereas the pulp contains lower amounts of allergens. Immuno localization showed they are primarily located in the cytosol but are subsequently excreted and finally accumulate at the plasmalemma-cell wall interface and in the cell wall. However, high discrepancies were observed in the content of allergens among, e.g. different cultivars of apple. As a consequence, the consumption of peeled-off fruits is recommended to reduce the risk of severe allergic reactions (anaphylactic shock) in individuals sensitized to Rosaceae fruits.

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