+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

A floating metal microelectrode array for chronic implantation

A floating metal microelectrode array for chronic implantation

Journal of Neuroscience Methods 160(1): 122-127

Implantation of multi-electrode arrays is becoming increasingly more prevalent within the neuroscience research community and has become important for clinical applications. Many of these studies have been directed towards the development of sensory and motor prosthesis. Here, we present a multi-electrode system made from biocompatible material that is electrically and mechanically stable, and employs design features allowing flexibility in the geometric layout and length of the individual electrodes within the array. We also employ recent advances in laser machining of thin ceramic substrates, application of ultra-fine line gold conductors to ceramic, fabrication of extremely flexible cables, and fine wire management techniques associated with juxtaposing metal microelectrodes within a few hundred microns of each other in the development of a floating multi-electrode array (FMA). We implanted the FMA in rats and show that the FMA is capable of recording both spikes and local field potentials.

(PDF emailed within 0-6 h: $19.90)

Accession: 012937566

Download citation: RISBibTeXText

PMID: 17067683

DOI: 10.1016/j.jneumeth.2006.09.005

Related references

A multiple floating microelectrode for chronic implantation and longterm single unit recording in the cat. Electroencephalography and Clinical Neurophysiology 58(3): 285-288, 1984

Spatial and temporal characteristics of V1 microstimulation during chronic implantation of a microelectrode array in a behaving macaque. Journal of Neural Engineering 9(6): 065003, 2013

Pre-implantation electrochemical characterization of a Parylene C sheath microelectrode array probe. Conference Proceedings 2012: 5126-5129, 2013

Electrically evoked potentials after subretinal implantation of the microelectrode array in rabbits. ARVO Annual Meeting Abstract Search & Program Planner : Abstract No 5070, 2003

Design, fabrication, and implantation of a dense array cortical microelectrode recording device. Society for Neuroscience Abstracts 24(1-2): 1125, 1998

Acute microelectrode array implantation into human neocortex: preliminary technique and histological considerations. Neurosurgical Focus 20(5): E4, 2006

A three-dimensional microelectrode array for chronic neural recording. IEEE Transactions on Bio-Medical Engineering 41(12): 1136-1146, 1994

Evaluation of a MEMS-based dual metal-layer thin-film microelectrode array for suprachoroidal electrical stimulation. IEEE Transactions on Neural Systems and Rehabilitation Engineering 21(4): 524-531, 2014

Microelectrode array for chronic deep-brain microstimulation and recording. IEEE Transactions on Bio-Medical Engineering 53(4): 726-737, 2006

A Multimodal, SU-8 - Platinum - Polyimide Microelectrode Array for Chronic In Vivo Neurophysiology. Plos One 10(12): E0145307, 2016

Fast wave propagation in auditory cortex of an awake cat using a chronic microelectrode array. Journal of Neural Engineering 4(2): 68-78, 2007

The use of a novel carbon nanotube coated microelectrode array for chronic intracortical recording and microstimulation. Conference Proceedings 2012: 791-794, 2013

A method of implantation and prolonged use of a microelectrode in a chronic experiment. Zhurnal Vysshei Nervnoi Deiatelnosti Imeni i P Pavlova 20(5): 1100-1101, 1970

Quantifying long-term microelectrode array functionality using chronic in vivo impedance testing. Journal of Neural Engineering 9(2): 026028, 2012

A bio-friendly and economical technique for chronic implantation of multiple microelectrode arrays. Journal of Neuroscience Methods 188(2): 187-194, 2010