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Observations on protective immunity in mice induced by recombinant Schistosoma japonicum Sj14FABP through several adjuvant formulations


Observations on protective immunity in mice induced by recombinant Schistosoma japonicum Sj14FABP through several adjuvant formulations



Chinese Journal of Schistosomiasis Control 19(1): 32-37



A study was conducted to determine the protective immunity in mice induced by recombinant S. japonicum Sj14FABP through several adjuvant formulations. The recombinant S. japonicum Sj14FABP was prepared by expression in E. coli as a GST fusion protein (rSjl4/GST). rSj14/GST was used to vaccinate outbred Kunming mice with complete Freund's adjuvant (FCA)/incomplete Freund's adjuvant (FIA), Bacillus Calmette-Gutrin (BCG) and immunostimulating complex (ISCOM).

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