Successful medical treatment of cutaneous aspergillosis in a premature infant using liposomal amphotericin B, voriconazole and micafungin
Santos, R.P.; Sánchez, P.J.; Mejias, A.; Benjamin, D.K.; Walsh, T.J.; Patel, S.; Jafri, H.S.
Pediatric Infectious Disease Journal 26(4): 364-366
2007
ISSN/ISBN: 0891-3668
PMID: 17414408
DOI: 10.1097/01.inf.0000258698.98370.89
Accession: 013065321
Treatment options for primary cutaneous aspergillosis in neonates are limited by the lack of pharmacokinetic and safety data of newer antifungal agents that are effective against Aspergillus spp. We report the successful treatment of cutaneous aspergillosis in an extremely low-birth-weight preterm infant with liposomal amphotericin B, voriconazole and micafungin, and provide pharmacokinetic profiles for voriconazole and micafungin.