+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

First report of diffuse cutaneous leishmaniasis and Leishmania amazonensis infection in Rio de Janeiro State, Brazil



First report of diffuse cutaneous leishmaniasis and Leishmania amazonensis infection in Rio de Janeiro State, Brazil



Transactions of the Royal Society of Tropical Medicine and Hygiene 101(7): 735-737



Diffuse cutaneous leishmaniasis (DCL) is characterised by multiple and progressive cutaneous lesions, resistance to chemotherapy and Leishmania-specific T-cell anergy. We report the first autochthonous DCL case and the first human infection with Leishmania amazonensis in Rio de Janeiro State, Brazil, where only L. braziliensis is considered to be the causative agent of cutaneous leishmaniasis. Leishmania amazonensis was identified by multilocus enzyme electrophoresis and PCR-RFLP. Our case was diagnosed as DCL according to clinical, parasitological, histopathological and immunological criteria. These observations indicate that L. amazonensis is increasing its geographical distribution in Brazil, accounting for unusual clinical presentations in new transmission areas.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 013245343

Download citation: RISBibTeXText

PMID: 17368698

DOI: 10.1016/j.trstmh.2007.01.005


Related references

In situ identification of Leishmania amazonensis associated with diffuse cutaneous leishmaniasis in Bahia, Brazil. Memorias do Instituto Oswaldo Cruz 84(4): 585-586, 1989

Draft Genome Sequences of Leishmania ( Leishmania ) amazonensis , Leishmania ( Leishmania ) mexicana , and Leishmania ( Leishmania ) aethiopica , Potential Etiological Agents of Diffuse Cutaneous Leishmaniasis. Microbiology Resource Announcements 8(20):, 2019

American cutaneous leishmaniasis in two cats from Rio de Janeiro, Brazil: first report of natural infection with Leishmania (Viannia) braziliensis. Transactions of the Royal Society of Tropical Medicine and Hygiene 98(3): 165-167, 2004

An autochthonous case of cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis Lainson & Shaw, 1972 from the north of Paraná State, Brazil. Memorias do Instituto Oswaldo Cruz 85(4): 475-476, 1990

An autochthonous case of cutaneous leishmaniasis caused by Leishmania (Leishmania) amazonensis Lainson & Shaw, 1972 from the north of Parana State, Brazil. Memorias do Instituto Oswaldo Cruzrecd 1991; 85(4): 475-476, 1990

Cutaneous leishmaniasis in Amazonia. Report of the 1st human case of mixed infection, determined by 2 different Leishmania species: Leishmania brasiliensis and Leishmania mexicana amazonensis. Revista do Instituto de Medicina Tropical de Sao Paulo 26(5): 272-275, 1984

Co-infection by Leishmania amazonensis and L. infantum/L. chagasi in a case of diffuse cutaneous leishmaniasis in Bolivia. Transactions of the Royal Society of Tropical Medicine and Hygiene 96(5): 529-532, 2002

Case Report: Atypical Cutaneous Leishmaniasis in a Patient with Mixed Leishmania guyanensis and Leishmania amazonensis Infection. American Journal of Tropical Medicine and Hygiene 99(5): 1165-1169, 2018

FIRST REPORT OF CUTANEOUS LEISHMANIASIS CAUSED BY Leishmania (Leishmania) infantum chagasi IN AN URBAN AREA OF RIO DE JANEIRO, BRAZIL. Revista do Instituto de Medicina Tropical de Sao Paulo 57(5): 451-454, 2016

Occurrence of American tegumentary leishmaniasis in the Mato Grosso do Sul State associated to the infection for Leishmania Leishmania amazonensis Ocorrencia de leishmaniose tegumentar americana no Estado do Mato Grosso do Sul associada a infeccao por Leishmania Leishmania amazonensis. Revista da Sociedade Brasileira de Medicina Tropical. Jan-Fev; 391: 43-46, 2006

Entomological surveys of Lutzomyia flaviscutellata and other vectors of cutaneous leishmaniasis in municipalities with records of Leishmania amazonensis within the Bragança region of Pará State, Brazil. Journal of Vector Ecology 43(1): 168-178, 2018

Cutaneous leishmaniasis due to Leishmania (Leishmania) amazonensis in Amazonian Brazil, and the significance of a negative Montenegro skin-test in human infections. Transactions of the Royal Society of Tropical Medicine and Hygiene 85(6): 735-738, 1991

Nipple involvement in diffuse cutaneous leishmaniasis (DCL) produced by Leishmania (L) amazonensis. Revista Da Sociedade Brasileira de Medicina Tropical 28(2): 139, 1995

Feline leishmaniasis due to Leishmania (Leishmania) amazonensis in Mato Grosso do Sul State, Brazil. Veterinary Parasitology 128(1-2): 41-45, 2005

Antigenic differences of Leishmania amazonensis isolates causing diffuse cutaneous leishmaniasis. Transactions of the Royal Society of Tropical Medicine and Hygiene 84(5): 678-680, 1990