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Action of alkaline extracts of the anterior lobe of the pituitary on immature female guinea-pigs

Action of alkaline extracts of the anterior lobe of the pituitary on immature female guinea-pigs

C.R. Soc. Biol 110: 19-21

Alkaline anterior pituitary extracts of oxen in quantities corresponding to 3.5 to 15 mg. of fresh gland produced definite ovarian changes in the immature guineapig. There was hypertrophy of the interstitial tissue and of the theca interna, with early degeneration of the granulosa and of the oocyte. In the larger follicles there were signs of luteinization.

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Accession: 013300412

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