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Prevention of adrenalectomy changes in the anterior pituitary of the rat by sodium chloride administration



Prevention of adrenalectomy changes in the anterior pituitary of the rat by sodium chloride administration



Anat Rec 79(3): 275-287



Ant. pituitaries of adrenalectomized [male] rats with and without supportive NaCl therapy were studied. The glands of normal animals given the same saline soln. over a similar period of time were included. The changes in the chromo-phil cells after adrenalectomy, reported previously, were con- firmed. The adm. of 1% NaCl to the adrenalectomized rat prevented in large part the pituitary changes characteristic of adrenal insufficiency. The adm. of 1% NaCl to the normal [male] rat resulted in some modifications in the ant. pituitary, namely increase in size and number of the chromophil cells.

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Accession: 013470888

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DOI: 10.1002/ar.1090790302


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