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Rickets in rats. 13. The effect of various levels and ratios of calcium to phosphorus in the diet upon the production of rickets



Rickets in rats. 13. The effect of various levels and ratios of calcium to phosphorus in the diet upon the production of rickets



J. Biol. Chem, 98: 207-214



13. Young rats were fed for 21 days on a vitamin D deficient diet, in which, by means of additions of calcium and phosphorus salts, the Ca: P ratio varied from 1 to 8. The bones were examined by X-rays, histologically and by ash analysis. Blood calcium and phosphorus were also determined. For a given ratio of Ca: P, increasing the salt level diminished the degree of rickets, increased the percentage of bone ash and (generally) increased serum phosphate.

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