+ Translate
+ Most Popular
Identification of compounds with anti-West Nile Virus activity
Geological age of the Ptilophyllum flora; a critical reassessment
Nira (Co 86032) - a new variety of sugarcane for Maharashtra
Occurrence of Eutrichophilus mexicanus (Rudow, 1866) and Eutrichophilus lobatus (Ewing, 1936) (Phthiraptera: Trichodectidae) on Sphiggurus villosus (Cuvier, 1825) (Rodentia: Erethizontidae) in Rio de
An assessment of water quality of river ganga at garhmukteshwar ghaziabad uttar pradesh india
The identity of the lipstick mold of cultivated mushrooms agaricus bisporus
Comparison of rice bran and maize bran as feeds for growing and fattening pigs
The composition of pampas-grass (Cortaderia argentea.)
Studies on feeding of tapioca thippi (tapioca or cassava starch waste) to swine
Effects of drum rolling on yield of summer groundnut
Integrated farming system for gardenland conditions of Coimbatore district - an over view
Influence of a decision analysis model on selection of drug therapy
Comparative performance of West Coast Tall and Lakshadweep Ordinary cultivars of coconut
Evaluation of WCT coconut and Komadan coconut
Cellars as hibernation sites for bats
Donkioporia expansa - A lesser known wood destroyer in buildings
The Bangla adaptation of Mini-Mental State Examination (BAMSE): An instrument to assess cognitive function in illiterate and literate individuals
Enterobacter amnigenus. An unusual human pathogen
'Rajeshwari' - a high-yielding white seeded variety of sesame for Andhra Pradesh
Gymnosperms of Sikkim, India
The great Coalinga cricket invasion
Psoriasis: correlation between severity index (PASI) and quality of life index (DLQI) in patients assessed before and after systemic treatment
Real-time PCR assays for the specific detection of monkeypox virus West African and Congo Basin strain DNA
Classification of fermented foods: worldwide review of household fermentation techniques
The biology of human starvation: some new insights

Some Biological Applications of Organometallic Compounds

Some Biological Applications of Organometallic Compounds

Science 93(2403): 47-50

ISSN/ISBN: 0036-8075

PMID: 17832843

DOI: 10.1126/science.93.2403.47

Organometallic compounds are compounds which have a metal directly attached to carbon, but only those of low chemical reactivity can, of course, have any immediate biological application. The more important applications are their use in the determination of structure and the synthesis of biologically significant materials like vitamins, hormones, haemoglobin, and chlorophyll, and in the treatment of infections and diseases of both plants and animals. Arsenic, antimony and bismuth coin-pounds have found wide' applications in the treatment of a variety of protozoan diseases-, As and Bi compounds have also been shown to be effective in the treatment of some forms of coccidiosis. Organogold compounds have been used, with indifferent success, in the treatment of TB. but with greater promise in the treatment of some forms of arthritis . Recent studies indicate that organolead compounds may be beneficial in the treatment of cancer, and germanium compounds are being examined in studies on pernicious anaemia. The pronounced effects of very small quantities of metals and their derivatives have given rise to the expression "oligodynamic action", e.g., 1 part of Cu in 100 million parts of distilled water will kill algae. Metals or their salts are widely distributed in plants and animals and the importance of trace elements in nutrition is well known.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 013500861

Download citation: RISBibTeXText

Related references

Therapeutic Applications Of Organometallic Compounds. Annals of the New York Academy of Sciences 125: 189-197, 1965

Group 9 organometallic compounds for therapeutic and bioanalytical applications. Accounts of Chemical Research 47(12): 3614-3631, 2014

Organometallic compounds in biological chemistry. Abel, E W And F G A Stone A Specialist Periodical Report: Organometallic Chemistry, Vol 13 A Review Of The Literature Published During 1983 Xv+491p The Royal Society Of Chemistry: London, England Illus 381-406, 1985

Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia 71(3): 92-101, 2017

Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia 71(5): 308, 2017

Laser photochemistry of organometallic compounds related to applications in microelectronics. Applied Organometallic Chemistry 3(5): 363-382, 1989

Biological activity of organometallic bismuth compounds. Biology of Metals 1(2): 69-76, 1988

Radical steps in the reactions of organometallic compounds with 2-methyl-2-nitrosopropane: experimental evaluation of the validity of the nitroxyl method for investigations of homolytic reactions of organometallic compounds. Russian Chemical Bulletin 43(5): 862-866, 1994

Applications of X-ray photoabsorption spectroscopy to the determination of local structure in organometallic compounds. Journal of the American Chemical Society 98(25): 8059-8069, 1976

Some Applications of Organosilicon and Organotin Compounds as Synthetic Intermediates in Organometallic Chemistry. Annals of the new York Academy of Sciences 239(1): 306-314, 1974

A new route to chelating bis(aryloxide) ligands and their applications to tantalum and titanium organometallic compounds. Inorganic Chemistry 43(2): 716-724, 2004

Speciation of molecular and ionic organometallic compounds in biological samples. Science of the Total Environment 71(1): 57-58, 1988

New Applications of Polyfunctional Organometallic Compounds in Organic Synthesis Frequently used abbreviations are defined at the end of the article. Angewandte Chemie 39(24): 4414-4435, 2000

Biological properties of transition-metal organometallic compounds. 3. beta-Ferrocenylalanine. Journal of Medicinal Chemistry 22(4): 424-428, 1979

Is water a friend or foe in organometallic chemistry? The case of group 13 organometallic compounds. Accounts of Chemical Research 34(3): 201-211, 2001