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The calcium and phosphorus content of the brain in experimental rickets and tetany



The calcium and phosphorus content of the brain in experimental rickets and tetany



J. Biol. Chem, 98: 625-636



Rickets in the rat is associated with a marked decrease of total Ca in the brain. For normal rats the Ca content of the brain was 100-260 (av. 182) mg. per 100 g. dry matter; for rachitic rats, 37-76 (av. 59) mg. Total P was not appreciably altered, but inorganic P decreased from 80.5 to 47.5 mg. These changes took place even on high Ca diet, and return to normal levels was slow.

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Accession: 013551091

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