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The excretory products of nitrogen breakdown and .their origin. 2. The end products of breakdown of nuclein and purine substances: the transformation of allantoin to urea in the organism of the lower mammals



The excretory products of nitrogen breakdown and .their origin. 2. The end products of breakdown of nuclein and purine substances: the transformation of allantoin to urea in the organism of the lower mammals



Trav. Soc. Chim. biol. 25: 1086-1092



The fate of allantoin in N metabolism was studied in the rat and rabbit. In the rat the distribution and amount of the various nitrogenous substances excreted in the urine, as urea, ammonia, allantoin, purine bases and uric acid, and creatinine and creatine, after intraperitoneal injection of allantoin in aqueous solution, was compared with the amounts of these substances present in the urine during control periods of 4 days preceding and following the 4-day injection period.

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