EurekaMag
+ Translate
+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Tabanidae
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep


Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep



Veterinary Research Communications 31(6): 749-755



ISSN/ISBN: 0165-7380

PMID: 17237985

DOI: 10.1007/s11259-007-0054-z

We report the results of investigations that were conducted in a sheep flock in Uttaranchal, India where repeated failure of anthelmintic medication was noted. The study revealed that Haemonchus contortus in sheep had developed resistance to benzimidazoles (fenbendazole, mebendazole and albendazole), imidazothiazole (levamisole) and salicylanide (rafoxanide), while it was fully susceptible to avermectins (ivermectin). Further, the suppression of nematode egg output in faeces of sheep naturally infected with multiple anthelmintic-resistant H. contortus following treatment with ivermectin tablet (0.4 mg/kg body weight (bw), orally), ivermectin injection (1% w/v, 0.2 mg/kg bw, subcutaneously) and ivermectin pour-on (0.5 w/v, 0.5 mg/kg bw) was also studied over a period of 10 weeks post treatment. It was noted that ivermectin tablet after initial clearance of infection (faecal egg count reduction 100%), could not prevent establishment of new patent natural infection for even a single day, while ivermectin pour-on and injection prevented the establishment of new infection for 7 and 14 days post treatment, respectively. Maximum protection period (duration for which mean faecal egg count of sheep reaches 500 eggs per gram of faeces or more) of 68 days was recorded in sheep treated with injectable ivermectin, followed by pour-on (60 days) and oral (53 days) preparations.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 013688751

Download citation: RISBibTeXText

Related references

Efficacy of monepantel and anthelmintic combinations against multiple-resistant Haemonchus contortus in sheep, including characterisation of the nematode isolate. Veterinary Parasitology 186(3-4): 513-517, 2012

Fecundity of anthelmintic resistant adult Haemonchus contortus after exposure to ivermectin or benzimidazoles in vivo. Research in Veterinary Science 50(2): 247-249, 1991

Changes in anthelmintic resistance status of Haemonchus contortus and Trichostrongylus colubriformis exposed to different anthelmintic selection pressures in grazing sheep. International Journal for Parasitology 19(1): 99-110, 1989

A novel approach to the control of anthelmintic-resistant Haemonchus contortus in sheep. Veterinary Parasitology 35(1-2): 61-69, 1990

Multiple anthelmintic resistance in Haemonchus contortus of sheep. Indian Journal of Animal Sciences 69(8): 547-549, 1999

The effect of molybdenum and sulphur on anthelmintic resistant Haemonchus contortus in sheep. Journal of the South African Veterinary Association 66(2): 44-46, 1995

Biological behaviour of anthelmintic resistant and susceptible strains of Haemonchus contortus in sheep. Indian Journal of Animal Sciences 70(11): 1112-1116, 2000

Multiple anthelmintic resistance in Haemonchus contortus on a sheep farm in Kenya. Veterinary Research Communications 21(7): 483-491, 1997

Multiple anthelmintic resistance in Haemonchus contortus on a sheep farm in India. Veterinary Parasitology 60(3-4): 355-360, 1995

Use of anthelmintic combinations against multiple resistant Haemonchus contortus in Angora goats. Small Ruminant Research 19(3): 281-283, 1996

Anthelmintic activity of cambendazole, mebendazole and parbendazole against a thiabendazole-resistant strain of Haemonchus contortus in sheep. Revista do Centro de Ciencias Rurais 10(4): 307-321, 1980

Anthelmintic activity of closantel against benzimidazole resistant strains of Haemonchus contortus and Trichostrongylus colubriformis in sheep. Australian Veterinary Journal 56(9): 461-462, 1980

The anthelmintic efficacy of fenbendazole against thiabendazole-resistant strains of Haemonchus contortus and Trichostrongylus colubriformis in sheep. Research in Veterinary Science 21(2): 232-237, 1976

Persistent anthelmintic activity of closantel against multiple resistance strain of Haemonchus contortus in sheep. Indian Journal of Animal Sciences 67(9): 770-771, 1997

Oral dosing with papaya latex is an effective anthelmintic treatment for sheep infected with Haemonchus contortus. Parasites and Vectors 4: 36, 2011