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Further observations on the improvement of polished rice with protein and amino acid supplements

Further observations on the improvement of polished rice with protein and amino acid supplements

Journal of Nutrition 57(3): 415-428

ISSN/ISBN: 0022-3166

PMID: 13272082

DOI: 10.1093/jn/57.3.415

The effects of various supplements of protein and amino acids on growth and on the deposition of liver fat in rats receiving a rice diet have been investigated and the imbalance created when the rice diet was supplemented with sufficient lysine to prevent the accumulation of liver fat has been studied in greater detail. A rice diet supplemented with 6% of various animal proteins supported an excellent rate of growth and maintained liver fat at normal levels. A supplement of several essential amino acids was required to give similar results. In short experiments (2 weeks) the retardation in growth caused by including 0.4% of L-lysine HCl in the rice diet was prevented by increasing the levels of leucine, isoleucine, valine and histidine. In longer experiments the growth retarding effect of additional lysine disappeared without the addition of other amino acids to the diet. Supplementation of the rice diet with various combinations of amino acids from which one or more of leucine, isoleucine, valine and histidine had been omitted resulted in a retardation of growth but in all instances in which the diet contained at least 0.4% of additional L-lysine-HCl the fat content of the liver approached a normal value. Even after 7 weeks fat accumulated in the liver unless the rice diet was supplemented with this level of lysine.

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Accession: 013718857

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Related references

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