+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma: results of a Belgian retrospective multicentre survey



Laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma: results of a Belgian retrospective multicentre survey



European Urology 51(6): 1633-8; Discussion 1638



To evaluate the technical and oncologic feasibility of laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma. A retrospective survey of 100 patients, treated with laparoscopic nephroureterectomy in 10 Belgian centres, was performed. Most procedures were performed transperitoneally. The distal ureter was managed by open surgery in 55 patients and laparoscopically in 45 patients. The mean follow-up was 20 mo. Mean operation time was 192 min and mean blood loss 234 ml. The conversion rate was 7%. Important postoperative complications were seen in 9%. Pathologic staging was pTa in 31 patients, pT1 in 23, pT2 in 12, pT3 in 33, and pT4 in 1, concomittant pTis in 3. Pathologic grade was G1 in 24 patients, G2 in 28, and G3 in 48. Negative surgical margins were obtained in all but one patient. Twenty-five patients developed progressive disease (24%) at a mean postoperative time of 9 mo (local recurrence in 8%, metastases in 11%, both in 5%). Progression was 0% for pTa, 17% for pT1, 17% for pT2, 51% for pT3, and 100% for pT4. Cancer-specific survival was 100% for pTa, 86% for pT1, 100% for pT2, 77% for pT3, and 0% for pT4. Laparoscopic nephroureterectomy appears to be a technically and oncologically feasible operation. To prevent tumour seeding, one should avoid opening the urinary tract and should extract the specimen with an intact organ bag. The high local recurrence rate in this study probably reflects the high percentage of high-grade and high-stage tumours in this study.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 013748878

Download citation: RISBibTeXText

PMID: 17055638

DOI: 10.1016/j.eururo.2006.09.016


Related references

The oncological results of laparoscopic nephroureterectomy for upper urinary tract transitional cell cancer are equal to those of open nephroureterectomy. Bju International 103(1): 66-70, 2009

Comparative study of oncologic outcome of laparoscopic nephroureterectomy and standard nephroureterectomy for upper urinary tract transitional cell carcinoma. Urology 69(3): 457-461, 2007

Hand-assisted laparoscopic nephroureterectomy versus open nephroureterectomy for the treatment of transitional-cell carcinoma of the upper urinary tract. Journal of Endourology 15(4): 391-5; Discussion 397, 2001

Laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma. Scandinavian Journal of Urology and Nephrology 40(4): 283-288, 2006

Laparoscopic nephroureterectomy for the treatment of transitional cell carcinoma of the upper urinary tract. Urology 57(3): 448-453, 2001

Place of laparoscopic nephroureterectomy in the treatment of upper urinary tract transitional cell carcinoma. Progres en Urologie 16(4): 413-417, 2006

Local reccurence following laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma. European Urology Suppl.s 2(1): 100, 2003

Hand-assisted laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma. Jsls 10(4): 432-438, 2007

Laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma: is it better than open surgery?. European Urology 46(6): 690-697, 2004

Radical laparoscopic nephroureterectomy for upper urinary tract transitional cell carcinoma: current status. Bju International 95(Suppl. 2): 68-74, 2005

Hand-assisted laparoscopic nephroureterectomy for the treatment of transitional cell carcinoma of the upper urinary tract. Urology 56(5): 741-747, 2000

Modified approach of hand-assisted laparoscopic nephroureterectomy for transitional cell carcinoma of the upper urinary tract. Urology 58(6): 930-934, 2001

Laparoscopic radical nephroureterectomy for upper urinary tract transitional cell carcinoma: Evaluation of oncological outcome. 2007

Total retroperitoneal laparoscopic nephroureterectomy with bladder-cuff resection for upper urinary tract transitional cell carcinoma. Journal of Investigative Surgery 27(6): 354-359, 2014

The role of laparoscopic nephroureterectomy in the management of upper urinary tract transitional cell carcinoma in comparing with the open procedure. European Urology Suppl.s 7(3): 259, 2008