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Chapter 13,876

The effects of sitosterol on serum lipids

Best, M.M.; Duncan, C.H.; Van Loon, E.J.; Wathen, J.D.

American Journal of Medicine 19(1): 61-70

1955


ISSN/ISBN: 0002-9343
PMID: 14388029
DOI: 10.1016/0002-9343(55)90274-6
Accession: 013875227

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Fourteen subjects, of whom 12 had high serum cholesterol levels, were allowed food to appetite and were given 6 to 8 g. of beta -sitosterol by mouth immediately before meals for from 13 to 64 weeks; the usual intake of beta -sitosterol was 20 to 25 g. daily. Fasting blood samples were analysed at intervals for total cholesterol, lipid P and total lipid. In 7 subjects the effect of sitosterol on serum lipoproteins, as estimated by ultracentrifuge, was studied.

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