Section 15
Chapter 14,031

Effects of fluoride and nonfluoride containing tin salts on the dental caries experience in children

Muhler, J.C.

Journal of Dental Research 37(3): 422-426


ISSN/ISBN: 0022-0345
PMID: 13539248
DOI: 10.1177/00220345580370031201
Accession: 014030017

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Groups of about 200 schoolchildren aged from 6 to 15 years had 4 topical applications of a 4 per cent, solution of stannous chlorofluoride, pH. 3. 5, or 2 per cent, of a solution of stannous sulfate complex, pH 1. 2, or distilled water; the children were re-examined after 6 and 12 months. Stannous chlorofluoride significantly reduced caries, DMF teeth and surfaces by 47 and 32. 5 per cent., respectively, after 6 months and 52 and 36. 5 per cent, after 12 months; the stannous sulfate complex gave a slight but not significant reduction. Studies with rat teeth in vivo and in vitro showed that in higher concentrations stannous sulfate complex was as effective as stannous fluoride in reducing solubility of enamel in acid.

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