Section 15
Chapter 14,069

High-performance liquid chromatography with atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for analysis of Angelica sinensis

Wang, Y-Li.; Liang, Y-Zeng.; Chen, B-Mei.

Phytochemical Analysis: Pca 18(4): 265-274


ISSN/ISBN: 0958-0344
PMID: 17623360
DOI: 10.1002/pca.968
Accession: 014068717

An HPLC-PAD-API/MS method for analysing the chemical constituents of Angelica sinensis (A. sinensis) has been developed. ESI and APCI spectra, in both positive ion (PI) and negative ion (NI) modes, provided very useful information concerning the molecular weights of detected compounds. By comparing the retention times, UV spectra, mass spectra and molecular weights of detected compounds with those published in literature, 15 constituents of A. sinensis could be tentatively identified. This technique involving combined MS information may provide an objective, reliable and rapid analytical method for the quality control and database research of traditional Chinese medicines.

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