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On the nutritive studies of pantothenic acid by antimetabolites. 1. Pantothenic acid deficiency produced by omega -methyl pantothenic acid in mice



On the nutritive studies of pantothenic acid by antimetabolites. 1. Pantothenic acid deficiency produced by omega -methyl pantothenic acid in mice



Tohoku J. Agric. Res, 10: 129-135



Male weanling mice were given a basal diet devoid of pantothenic acid and supplemented with sodium omega -methylpantothenate and calcium pantothenate in different amounts and proportions for 16 days, after which they had the basal diet alone. Depression of weight gain increased with the amount of w-methylpantothenic acid given, but the effect depended more on the ratio of omega -methylpantothenic acid to pantothenic acid than on the absolute amounts of the antagonist.

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