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Ornithine as a precursor for the pyrrolidine ring of nicotine



Ornithine as a precursor for the pyrrolidine ring of nicotine



Biochimica et Biophysica Acta 33(1): 22-26



Radioactive nicotine, from Nicotiana rustica plants which had been fed (2-14C)-ornithine, was degraded with recovery of C-5 of the pyrrolidine ring. This position of the ring was shown to have about half of the radioactivity of the original nicotine. The remaining radioactivity was in the residual carbon skeleton of the nicotine, which was isolated as a derivative of a substituted primary amine.

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Accession: 014133433

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PMID: 13651178

DOI: 10.1016/0006-3002(59)90492-5


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