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Recessive buphthalmos in the rabbit



Recessive buphthalmos in the rabbit



Genetics 47: 519-529



Data from rabbit litters segregating for the recessive eye abnormality buphthalmos ob-tained from the breeding and litter records at the Hamilton Station, Roscoe B. Jackson Memorial Laboratory, were analyzed to ascertain variables affecting the penetrance of the abnormality in this colony. Maternal age and litter birth order are shown to be unrelated to the occurrence of buphthalmos in these litters. Among litters of large size there is a deficiency of litters containing a large number of affected animals and an excess of litters containing no buphthalmic animals. There is an excess of stillborn females in those litters from carrier parents in which no buphthalmos appears. The birth weight of buphthalmic females is significantly greater than that of their normal female siblings, but the birth weights of normal and buphthalmic males do not differ. It is suggested that buphthalmos may be a frequently occurring symptom of a systemic developmental defect in rabbits.

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Accession: 014163047

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PMID: 13904370


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