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Reduced growth hormone content in anterior pituitaries of rats on protein-free diets



Reduced growth hormone content in anterior pituitaries of rats on protein-free diets



Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine 101(1): 97-99



Anterior pituitaries of protein-depleted and of control female rats were bioassayed for growth-stimulating activity. Absence of dietary protein for 5 weeks reduced growth hormone content of hypophysis to 1/4 that found in normal glands or 1/2 normal amount/mg tissue. There was a parallel decrease in number and size of pituitary acidophils. Growth-promoting potency could be detected in plasma of protein-depleted animals but appeared to be reduced below normal levels.

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Accession: 014163893

Download citation: RISBibTeXText

PMID: 13658203

DOI: 10.3181/00379727-101-24844


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