Sitosterol administration in normal and hypercholesteremic subjects; the effect in man of sitosterol therapy on serum lipids and lipoproteins
Sachs, B.A.; Weston, R.E.
A.M.A. Archives of Internal Medicine 97(6): 738-752
1956
ISSN/ISBN: 0888-2479 PMID: 13312715 Accession: 014185489
Serum cholesterol fell in 5 normal human subjects given a mixture of beta - and dihydro- beta -sitosterols immediately before meals, but rose in some patients with disorders of lipid metabolism. Sitosterol reduced the serum cholesterol concentration and arrested the growth of xanthomata in a subject with xanthomatosis.
PDF emailed within 1 workday: $29.90
Related References
Ju, Y.H.; Clausen, L.M.; Allred, K.F. 2004: B-Sitosterol, b-Sitosterol Glucoside, and a Mixture of b-Sitosterol and b-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice The Journal of Nutrition 134(5): 45-51Ju, Y.H.; Clausen, L.M.; Allred, K.F.; Almada, A.L.; Helferich, W.G. 2004: -Sitosterol, -Sitosterol Glucoside, and a Mixture of -Sitosterol and -Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells In Vitro and in Ovariectomized Athymic Mice The Journal of Nutrition 134(5): 1145-1151
Barber, J.M.; Grant, A.P. 1955: The serum cholesterol and other lipids after administration of sitosterol British Heart Journal 17(3): 296-298
Weisweiler, P.; Heinemann, V.; Schwandt, P. 1984: Serum lipoproteins and lecithin: cholesterol acyltransferase (LCAT) activity in hypercholesterolemic subjects given β-sitosterol International Journal of Clinical Pharmacology, Therapy and Toxicology (1980) 22(4): 204-206
Weisweiler, P.; Heinemann, V.; Schwandt, P. 1984: Serum lipoproteins and lecithin: cholesterol acyltransferase (LCAT) activity in hypercholesterolemic subjects given beta-sitosterol International Journal of Clinical Pharmacology Therapy and Toxicology 22(4): 204-206
Bhattacharyya, A.K.; Connor, W.E.; Lin, D.S.; McMurry, M.M.; Shulman, R.S. 1991: Sluggish sitosterol turnover and hepatic failure to excrete sitosterol into bile cause expansion of body pool of sitosterol in patients with sitosterolemia and xanthomatosis Arteriosclerosis and Thrombosis: a Journal of Vascular Biology 11(5): 1287-1294
Ju, Y.H.; Clausen, L.M.; Allred, K.F.; Almada, A.L.; Helferich, W.G. 2004: Beta-Sitosterol, beta-Sitosterol Glucoside, and a Mixture of beta-Sitosterol and beta-Sitosterol Glucoside Modulate the Growth of Estrogen-Responsive Breast Cancer Cells in Vitro and in Ovariectomized Athymic Mice Journal of Nutrition 134(5): 1145-1151
Best, M.M.; Duncan, C.H.; Van Loon, E.J.; Wathen, J.D. 1955: The effects of sitosterol on serum lipids American Journal of Medicine 19(1): 61-70
Kaegi, P.; Koller, F. 1957: The influence of sitosterol on serum lipids Helvetica Med Acta 24(4): 392-397
Cicero, A.F.G.; Fiorito, A.; Panourgia, M.P.nagiota 2002: Effects of a new soy/b-sitosterol supplement on plasma lipids in moderately hypercholesterolemic subjects Journal of the American Dietetic Association 102(12): 07-11
Cicero, A.F.G.; Fiorito, A.; Panourgia, M.Panagiota.; Sangiorgi, Z.; Gaddi, A. 2002: Effects of a new soy/beta-sitosterol supplement on plasma lipids in moderately hypercholesterolemic subjects Journal of the American Dietetic Association 102(12): 1807-1811
Riley, F.P.; Steiner, A. 1957: Effect of sitosterol on the concentration of serum lipids in patients with coronary atherosclerosis Circulation 16(5): 723-729
Nnamani, E.M.; Akah, P.A.; Okoli, C.O.; Ezike, A.C.; Kenne, M.T. 2020: Gastroprotective Effects of β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside from Bridelia ferruginea Stem Bark American Journal of Pharmacology and Toxicology 15(1): 29-39
Allais, JP.; Alcaide, A.; Barbier, M. 1973: Fucosterol-24, 28 Epoxide and 28-oxo- ss-sitosterol as possible intermediates in the conversion of ss-sitosterol into cholesterol in the locust Locusta migratoria L Experientia 298: 944-945
Vo, T.K.; Ta, Q.T.H.; Chu, Q.T.; Nguyen, T.T.; Vo, V.G. 2020: Anti-Hepatocellular-Cancer Activity Exerted by β-Sitosterol and β-Sitosterol-Glucoside from Indigofera zollingeriana Miq Molecules 25(13)
Nishioka, I; Ikekawa, N; Yagi, A; Kawasaki, T; Tsukamoto, T 1965: Studies on the Plant Sterols and Triterpenes. II. Separation of Stigmasterol, b-Sitosterol and Campesterol, and about So-called "-Sitosterol." Chemical and Pharmaceutical Bulletin 13(3): 379-384
Tsukamoto, T.; Et Al 1958: Studies on the sterols from Phellodendron amurense Rupr. (1). Isolation of beta-sitosterol and gamma-sitosterol. J. pharm. Soc. Japan. 78: 10, 1099-1101
Van Vo, G.; Guest, P.C.; Nguyen, T.T.; Vo, T.K. 2022: Evaluation of Anti-Hepatocellular-Cancer Properties of β-Sitosterol and β-Sitosterol-Glucoside from Indigofera zollingeriana Miq Methods in Molecular Biology 2343: 229-240
Allais, J.P.; Alcaide, A.; Barbier, M. 1973: Fucosterol-24,28 epoxide and 28-Oxe-β-sitosterol as possible intermediates in the conversion ofβ-sitosterol into cholesterol in the locust Locusta migratoriaL Cellular and Molecular Life Sciences 29(8): 944-945
Yuan, C.; Zhang, X.; Long, X.; Jin, J.; Jin, R. 2019: Effect of β-sitosterol self-microemulsion and β-sitosterol ester with linoleic acid on lipid-lowering in hyperlipidemic mice Lipids in Health and Disease 18(1): 157