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Aflatoxin detoxification: hydroxydi-hydro-aflatoxin B1

Aflatoxin detoxification: hydroxydi-hydro-aflatoxin B1

Appl. Microbiol 16(4): 665-666

Non-enzymatic production of a new fluorescing compound with concomitant disappearance of aflatoxin B1 was noted when the latter was added to acid-producing mould cultures or, subsequently, when added to 0.1 N citric acid which was then agitated at 28 degrees C for 24-48 hr. The compound was isolated and shown, by duckling tests, to be less toxic than aflatoxin B1. Bile duct hyperplasia was not noted but there was some fatty metamorphosis of the liver.

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Accession: 014333490

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PMID: 5647527

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