Effect of alcohol on the livers of rats. 1. Effect of a single intoxicating dose of alcohol on the livers of rats fed a choline-def icient diet or a commercial ration

Takeuchj, J.; Takada, A.; Ebata, K.; Sawae, G.; Okumura, Y.

Lab. Invest 19: 211-217


Accession: 014431770

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For 5 weeks female Wistar rats were given a diet deficient in choline or a stock diet, each with or without isocaloric solutions of ethanol, 1.5 ml per 100 g bodyweight, or of glucose by stomach tube at different intervals after which serum glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT) and lactic dehydrogenase (LD) activities and cholesterol, triglyceride and phospholipid in the liver were estimated.