Effect of dietary level of protein on serum cholesterol, serum lecithin-cholesterol acyltransferase activity and on faecal sterol and bile acid excretion in the rat
Nath, N.; Singh, B.
Indian Journal of Biochemistry 7(4): 267-270
ISSN/ISBN: 0019-5081 Accession: 014434577
Male adult albino rats of weight 121 to 128 g were given a basal diet supplying 12, 20 or 42% protein alone or with 0.5% cholesterol or 0.25% cholic acid. Dietary protein at 42% gave the highest serum cholesterol, 64.8 mg/100 ml; lecithin cholesterol acyltransferase (LCAT) activity, 9.7 mg cholesterol esterified by 100 ml serum in 24 h; and increased average daily faecal excretion of bile acids in rats fed on diets without cholesterol and cholic acid for 33 days.