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Effects of selenium and vitamin E on nutritional muscular dystrophy in lambs

Effects of selenium and vitamin E on nutritional muscular dystrophy in lambs

Journal of Animal Science 27(3): 751-756

Sixty-four lambs were weaned at 2 days of age and were used in 2 factorial studies with vitamin E and Se. A semi-purified diet in which Torula yeast was the source of protein was prepared and fed as a milk substitute. When this diet was fed, Se and vitamin E had an additive effect on reduction of blood level of GOT [glutamic oxaloacetic transaminase], increasing survival time, and decreasing the ratio of urinary creatine to creatinine excretion. Vitamin E reduced LDH [lactic acid dehydrogenase] values and prevented hemo-lysis of red blood cells by dialuric acid. Se enhanced hemolysis which was probably related to increased survival and resulting depletion of vitamin E stores. Se increased the growth rates of lambs in one experiment while vitamin E had no effect in either experiment.

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Accession: 014454482

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PMID: 5691010

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