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Human biotin deficiency. A case history of biotin deficiency induced by raw egg consumption in a cirrhotic patient



Human biotin deficiency. A case history of biotin deficiency induced by raw egg consumption in a cirrhotic patient



American Journal of Clinical Nutrition 21(2): 173-182



A white woman 62 years old developed clinical signs of biotin deficiency after consuming a diet containing 6 raw eggs daily for 18 months after diagnosis of liver cirrhosis. Whole blood biotin before treatment was 0.25ng per ml. All symptoms cleared or improved markedly after treatment for 2 to 5 days with 200 micro g biotin by muscle daily with her pre-treatment diet. Anaemia, muscle pains, hypercholesterolaemia and electrocardiographic abnormality were absent.

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Accession: 014509293

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PMID: 5642891



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