Human Disposition of Antimony Administered as Antimony Sodium Dimercapto-Succinate. With an Analysis of Antimony Concentration in Excreted Schistosoma Haematobium Ova

Schulert, A.R.; Browne, H.G.; Salem, H.H.

Transactions of the Royal Society of Tropical Medicine and Hygiene 58: 48-52


ISSN/ISBN: 0035-9203
PMID: 14117554
DOI: 10.1016/0035-9203(64)90067-7
Accession: 014509308

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Antimony sodium dimercaptosuccinate labelled with Sb124 was given to 6 patients excreting appreciable numbers of Schistosoma haematobium eggs in the urine. After one dose of 13-6 mg. per kg. body-weight about 20% was excreted in the urine in the first 2 hours and 35% during the first 24 hours. Excretion then continued slowly for a long time, measurable quantities still being present in the urine after 5 weeks.