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Immunization Against Aujeszky's Disease With Live Vaccine. I. Attenuation Of Virus And Some Properties Of Attenuated Strains






Acta Virologica 8: 1-9

Immunization Against Aujeszky's Disease With Live Vaccine. I. Attenuation Of Virus And Some Properties Of Attenuated Strains

Rapid passage in chick embryo cells (C.E.C. ; yielded a modified pseudorahies virus stra; n ("BUK") which produced rapid degeneration of CFC tures had high infectivity. formed large plaques in CEC plate cultures and killed intramuscuarly infected rabbits without any signs pruntus fication of the properties of the virus in CFC was also demonstrated in another two strains. One strain. ("SUCH-1") was selected from among 20 freshly isolated virus strains.


Accession: 014512929

PMID: 14106017



Related references

Skoda, R.; Brauner, I.; Sadecky, E.; Somogyiova, J., 1963: A live attenuated virus (BUK) for immunization of pigs against Aujeszky's disease.. By passage in chick embryo cell culture, the virus lost its neurotropism and pathogenicity for pigs, whilst retaining its immunizing properties.

Chumakov, M.P.; E.A., 1959: Preliminary report on mass oral immunization of the population against poliomyelitis with live virus vaccine from attenuated strains of Sabin vaccine. On the basis of the results of epidemiological, clinical and laboratory investigations it can be concluded that immunization with live vaccine from attenuated Sabin strains of types I, II and III produces no harmful effects. The safety of mass vac...

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