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Infection of small laboratory animals with Mycoplasma mycoides var. capri and Mycoplasma mycoides var. mycoides



Infection of small laboratory animals with Mycoplasma mycoides var. capri and Mycoplasma mycoides var. mycoides



Vet. Rec 77: 1527-1528



Mice were infected with Mycoplasma caprae by i/p inoculation of a 48-hour culture grown in BVF-OS medium and mixed with a mucin suspension. Almost all mice became visibly ill and multiplication of the organism was associated with positive blood cultures. Although the majority recovered, a proportion died with signs of peritonitis and pleural effusion. No effects occurred in control mice receiving inocula containing no mucin. Severe fibrinous pleurisy and pericarditis occurred in 11 of 16 rabbits inoculated intrathoracically with mucin-containing suspensions of M. caprae or M. mycoides. The exact role of mucin in the intrathoracic infection of rabbits is not clear; severe fibrinous pleurisy was occasionally seen after administration of inocula containing no mucin.

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Accession: 014520084

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PMID: 5849749


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