Studies on fatty acid esters of flavins. VI. Incorporation of riboflavin part of riboflavin tetrabutyrate-2-14C into flavin nucleotides in the organs of rat
Yagi, K.; Yamada, M.; Okuda, J.
Journal of Vitaminology 15(2): 155-159
1969
ISSN/ISBN: 0022-5398
PMID: 5347449
Accession: 014689098
For parts 4 and 5 see Abst. 5675, Vol. 35 and Title 2496, Vol. 38. 6. Rats were given by mouth in soya bean oil riboflavin 2', 3', 4', 5'-tetrabutyrate-2-14C equivalent to 400 micro g riboflavin. The amounts of total flavin in liver, kidney, heart and small intestine after 72 h were similar to those in the normal rat. Specific radioactivities were not greatly different from each other. The amounts and activities of riboflavin, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) are tabulated. Values obtained 72 h after rats were given the compound subcutaneously were not greatly different. Results show that the labelled compound was hydrolysed to riboflavin which was incorporated into FMN and FAD.