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Tetramisole (R 8299), a new, potent broad spectrum antnehnintic

Tetramisole (R 8299), a new, potent broad spectrum antnehnintic

Nature, Lond., 209: 1084-1086

In chickens, a single oral dose of tetramisole (the hydrochloride of 2, 3, 5, 6-tetrahydro-6-phenylimidazo thiazole), 40 mg./kg. body wt., expelled 97-100% of all forms of Ascaridia galli, Heterakis gallinarum and Capillaria obsignata within 24 hours, with no depression of egg production. At 5-20 mg. per kg., tetramisole was fully effective against several nematodes in lambs, sheep and cattle.

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