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The genetic extent of the insertion involved in the flecked translocation in the mouse



The genetic extent of the insertion involved in the flecked translocation in the mouse



Genetics 55(2): 203-212



By the expression of various recessive alleles located in autosome I in relation to Type I and Type II animals, the fd translocation in the house mouse involves an insertion from the middle region of chromosome I into the X chromosome. The genes fr and pu have been mapped outside the region of insertion whereas sh-1 is located inside this region. Type I males carrying sh-l+ in the Xfd chromosome and sh-1 in autosome I do not show any effect of shaker-1, while some of the Type I females become deaf. Type II females carrying sh-l+ on the Xfd chromosome and sh-1 on both of their autosomes I, show a low intensity of shaking behavior and most of them become deaf. The condition with Type II males is unknown because of their low viability in the backcross generations.

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Accession: 014745068

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PMID: 6029966


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