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A factor toxic to crustacean in the venom of the scorpion Androctonus australis Hector


A factor toxic to crustacean in the venom of the scorpion Androctonus australis Hector



Toxicon: Official Journal of the International Society on Toxinology 10(3): 211-216



ISSN/ISBN: 0041-0101

PMID: 5072085

DOI: 10.1016/0041-0101(72)90005-0

Pure neurotoxins separated from the venom of the scorpion Androctonus australis Hector and highly toxic to mammals are inactive when tested on several arthropods. The fly larvae toxin originating from the same venom demonstrates a strong toxicity to insects but is completely inactive when applied to an arachnid or a crustacean. Recycling gel filtration, on Sephadex G-50, of the crude venom allows the isolation of a product exhibiting a high paralyzing and lethal activity to a crustacean. The toxic activity is destroyed by trypsin digestion. It is concluded that, in addition to the toxins active in mammals and insects, the venom of A. australis contains another discrete protein specifically active on a crustacean.

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Accession: 014855447

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