A preliminary test of the protective efficacy of permethrin-treated bed nets in an area of Anopheles gambiae metabolic resistance to pyrethroids in north Cameroon
Etang, J.; Chouaibou, M.; Toto, J.-C.; Faye, O.; Manga, L.; Samè-Ekobo, A.; Awono-Ambene, P.; Simard, F.éd.ér.
Transactions of the Royal Society of Tropical Medicine and Hygiene 101(9): 881-884
2007
ISSN/ISBN: 0035-9203
PMID: 17632192
DOI: 10.1016/j.trstmh.2007.05.012
Accession: 014897604
A trial of permethrin-treated nets (PTNs) versus untreated nets (UTNs) was conducted in Pitoa (north Cameroon), where the main malaria vectors, Anopheles gambiae s.l. and Anopheles arabiensis, show metabolic-based permethrin resistance. The deterrent effect of permethrin greatly reduced A. gambiae biting rate inside rooms where PTNs were installed. After 3 months of net use, malaria reinfection rate was significantly lower in children sleeping under a PTN, but no such effect was observed after 6 months. Parasitaemia was not significantly different between the two arms. These findings suggest good, although transitory, personal protection against malaria conferred by PTNs in an area of metabolic-based permethrin resistance.