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Ameloblastic carcinoma: an analysis of 14 cases



Ameloblastic carcinoma: an analysis of 14 cases



Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics 103(6): 799-807



To present the classifications of malignant ameloblastomas, provide histopathologic guidelines for the diagnosis of ameloblastic carcinoma, and discuss treatment and long-term follow-up. Fourteen archival specimens of ameloblastic carcinoma with detailed treatment and follow-up documentation were identified by the authors. Traditional methods of microscopic observation form the basis for diagnosis. Histopathologic features of ameloblastic carcinoma include lack of differentiation, hypercellularity, high mitotic index, vascular invasion, and neural invasion. The long-term follow-up findings in this study support the concept that aggressive surgical intervention provides the best chance for survival. Patients treated otherwise had recurrence. The patients with the highest number of recurrences did not survive the disease.

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Accession: 015002294

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PMID: 17448710

DOI: 10.1016/j.tripleo.2006.11.048


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