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Amino acid transport in Neurospora crassa. IV. Properties and regulation of a methionine transport system


, : Amino acid transport in Neurospora crassa. IV. Properties and regulation of a methionine transport system. Biochimica et Biophysica Acta 233(1): 201-214

A specific amino acid transport system in Neurospora crassa is described with affinity for methionine and several of its analogs. This methionine transport system has a Michaelis constant (Km) for l-methionine of about 23 M and has lower affinity for S-ethylcysteine, ethionine, S-methylcysteine and norleucine.


Accession: 015005258

PMID: 5579132

DOI: 10.1016/0005-2736(71)90372-5

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Related references

Pall, M.L., 1970: Amino acid transport in Neurospora crassa. II. Properties of a basic amino acid transport system. Studies of amino acid uptake have revealed the existence of an active transport system in Neurospora crassa specific for basicl-amino acids. This system, designated amino acid transport system III, has a Michaelis constant for l-lysine uptake of 4...

DeBusk, R.M.; DeBusk, A.G., 1980: Physiological and regulatory properties of the general amino acid transport system of Neurospora crassa. The fundamental properties of the general amino acid transport system of Neurospora crassa were investigated in the conidial stage of the life cycle. The transport activity was found to be under genetic control, and an isogenic set of mutants defi...

Stuart, W.D.; Debusk, A.G., 1971: Molecular transport. I. In-vitro studies of isolated glycoprotein subunits of the amino acid transport system of Neurospora crassa conidia. Archives of Biochemistry and Biophysics 144(2): 512-518

Stuart, W.; Debusk, A., 1971: Molecular transport. I. In vitro studies of isolated glycoprotein subunits of the amino acid transport system of Neurospora crassa conidia. Neurospora crassa conidia have constitutive transport systems for neutral and basic amino acids. KCl-extracted conidia show reduced l-arginine transport. KCl extracts contain several molecular species, some of which will bind l-amino acids. Purifi...

Pall, M.L., 1969: Amino acid transport in Neurospora crassa. I. Properties of two amino acid transport systems. Biochimica et Biophysica Acta 173(1): 113-127

Stuart W.D.; Debusk A.G., 1971: Molecular transport part 1 in vitro studies of isolated glyco protein sub units of the amino acid transport system of neurospora crassa conidia. Archives of Biochemistry & Biophysics 144(2): 512-518

Tisdale, J.H.; DeBusk, A.G., 1970: Developmental regulation of amino acid transport in Neurospora crassa. Conidia of Neurospora crassa exhibit an ability to transport various amino acids against a concentration gradient. The conidial transport system has previously been characterized in terms of kinetics, competitions, and genetic control. This study...

Tisdal, Janet-Boone-Herbert, 1972: Mechanisms of developmental regulation of amino acid transport in Neurospora crassa

Thwaites, W.M.; Pendyala, L., 1969: Regulation of amino acid assimilation in a strain of Neurospora crassa lacking basic amino acid transport activity. Biochimica et Biophysica Acta 192(3): 455-461

Wolfinbarger, L.; D.B.sk, A.G., 1971: An inducible amino acid transport system in Neurospora crassa. The general amino acid transport system in Neurospora crassa conidia is shown to be stimulated to a greater rate of transport activity by the basic amino acids L-arginine and L-lysine. The neutral amino acid L-phenylalanine causes a reduction in t...