EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture


Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture



World Journal of Gastroenterology 13(41): 5432-5439



ISSN/ISBN: 1007-9327

PMID: 17907285

AIM: To investigate the multicellular resistance of human hepatocellular carcinoma HepG2 cells in three-dimensional culture to delisheng, 5-fluorouracil and adriamycin, and the possible molecular mechanisms of delisheng. METHODS: Human hepatocellular carcinoma HepG2 cells were cultured with a liquid overlay technique. After the formation of multicellular spheroids, morphology was analyzed by phase contrast microscopy, scanning electron microscopy and transmission electron microscopy.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 015270104

Download citation: RISBibTeXText

Related references

Delisheng Injection (), a Chinese medicinal compound, enhanced the effect of cis-platinum on lung carcinoma cell line PGCL3. Chinese Journal of Integrative Medicine 20(4): 286-291, 2014

Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2. Cytotechnology 64(1): 43-51, 2012

Anti-endostatin monoclonal antibody inhibits antiangiogenic activity of endogenous endostatin secreted from human hepatocellular carcinoma xenografted in nude mice and promotes growth of the tumor by suppression of apoptosis. Hepatology 34(4 Pt 2): 387A, 2001

Antiproliferative Activity of the Chinese Medicinal Compound, Delisheng, Compared With Rg3 and Gemcitabine in HepG2 Cells. Indian Journal of Pharmaceutical Sciences 75(5): 578-584, 2013

Delisheng, a Chinese medicinal compound, exerts anti-proliferative and pro-apoptotic effects on HepG2 cells through extrinsic and intrinsic pathways. Molecular Biology Reports 37(7): 3407-3412, 2010

Anti-endostatin monoclonal antibody inhibits endogenous endostatin secreted from human hepatocellular carcinoma xenografted in nude mice and promotes the growth of the tumor itself. International Journal of Cancer Suppl (13): 130, 2002

Mouse endostatin secreted by a human colon carcinoma cell line and a murine renal carcinoma cell line inhibits and immortal endothelial cell line in vitro and flank tumor growth in mice. Proceedings of the American Association for Cancer Research Annual Meeting 40: 621, 1999

Inhibitory effect of mycophenolate mofetil on human hepatocellular carcinoma cell line HepG-2. Journal of Medical Colleges of Pla 24(4): 208-214, 2009

Anti-endostatin monoclonal antibody enhances growth of human hepatocellular carcinoma cells by inhibiting activity of endostatin secreted by the transplanted cells in nude mice. International Journal of Oncology 25(5): 1267-1271, 2004

Effects of silibinin on cell growth and invasive properties of a human hepatocellular carcinoma cell line, HepG-2, through inhibition of extracellular signal-regulated kinase 1/2 phosphorylation. European Journal of Pharmacology 591(1-3): 13-20, 2008

An Integrative Serum Pharmacology-Based Approach to Study the Anti-Tumor Activity of B. paniculatum Aqueous Bulb Extract on the Human Hepatocellular Carcinoma Cell Line BEL-7404. Frontiers in Pharmacology 11: 01261, 2020

Apoptosis in anti-tumor effect of irinotecan is mediated by P53 in human hepatocellular carcinoma cell line. Clinical Pharmacology and Therapeutics 75(2): P60, 2004

Enhancement of cytotoxic and pro-apoptotic effects of 2-aminophenoxazine-3-one on the rat hepatocellular carcinoma cell line dRLh-84, the human hepatocellular carcinoma cell line HepG2, and the rat normal hepatocellular cell line RLN-10 in combination with 2-deoxy-D-glucose. Oncology Reports 27(2): 347-355, 2012

Cecropin-P17, an analog of Cecropin B, inhibits human hepatocellular carcinoma cell HepG-2 proliferation via regulation of ROS, Caspase, Bax, and Bcl-2. Journal of Peptide Science: An Official Publication of the European Peptide Society 21(8): 661-668, 2015

Inhibitory effect of compound cantharides capsule on the proliferation of xenografts of human hepatocellular carcinoma HepG(2)215 in mice. Zhonghua Zhong Liu Za Zhi 34(11): 821-825, 2012