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Direct pituitary effects of neonatal androgenization on the LHRH response of dispersed pituitary cell cultures


, : Direct pituitary effects of neonatal androgenization on the LHRH response of dispersed pituitary cell cultures. Developments in endocrinology2(12): 503-505


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O'Conner, J.L.; Wolfe, R.R.; Allen, M.B.; Mahesh, V.B., 1982: Effect of neonatal androgenization on the LHRH response of dispersed pituitary cell cultures. To determine if neonatal androgenization affects pituitary luteinizing hormone releasing hormone (LHRH) response, female rats were androgenized 24-48 hr following birth. Intact male and female litter mates were maintained for comparison. At 83 day...

Tang, L.K.; Martellock, A.C.; Horiuchi, J.K., 1982: Estradiol stimulation of LH response to LHRH and LHRH binding in pituitary cultures. Data are presented with indicate that the effect of priming with oestradiol-17 beta on rat pituitary LH response to LHRH is associated initially with an increase in cellular LH content and is later associated with increases in LHRH binding and in...

Kaur, A.; Saxena, R.N., 1994: Changes in the pituitary and plasma LH, hypothalamic LHRH and pituitary response to LHRH in aging Swiss albino mice. In the present study changes in the secretion of hypothalamus and pituitary are reported in aging mice. Hypothalamic Luteinizing hormone releasing hormone (LHRH) and pituitary and plasma Luteinizing hormone (LH) were estimated by radioimmunoassay...

Tang L.K.; Martellock A.C.; Horiuchi J.K., 1982: Estradiol stimulation of luteinizing hormone response to lhrh and lhrh binding in pituitary cultures. The relationship between 17.beta.-estradiol (E2) stimulation of luteinizing hormone (LH) response to LHRH and E2 effect on LHRH binding was examined in pituitary monolayer cultures prepared from female rats. E2 pretreatment significantly (P < 0...

Ulloa-Aguirre, A.; Damián-Matsumura, P.; Espinoza, R.; Dominguez, R.; Morales, L.; Flores, A., 1990: Effects of neonatal androgenization on the chromatofocusing pattern of anterior pituitary FSH in the female rat. Anterior pituitary glands were removed from neonatally androgenized (100 .mu.g testosteone propionate) female rats and normal controls at 5, 10, 18, 21, 30, 60 and 90 days of age, and the multiple froms of FSH present within them were separated by...

de Souza Valle, L.B.; Denti, A.; Oliveira-Filho, R.M., 1981: Effects of neonatal castration and androgenization on the contents of androgen-binding sites of rat pituitary. Archives Internationales de Physiologie et de Biochimie 89(1): 85-87

Yeo T.; Grossman A.; Belchetz P.; Besser G.M., 1981: Response of luteinizing hormone from columns of dispersed rat pituitary cells to a highly potent analog of lhrh. The response of LH [luteinizing hormone] from a perfused column of dispersed rat anterior pituitary cells to LHRH and the analog, D-Ser(But)6-desGly10-Proethylamide9-LHRH (Hoe 766), a possible contraceptive agent, was investigated. Dose-response c...

Vanderstichele H.; Eechaute W.; Lacroix E.; Leusen I., 1987: The effects of neonatal androgenization of male rats of testosterone metabolism by the hypothalamus pituitary gonadal axis. Male rats were androgenized on the third postnatal day by a single injection of 1 mg testosterone propionate. The in vitro metabolism of [4-14C]testosterone by pituitary and hypothalamus homogenates was investigated at the age of 90 days. The pitu...

Vanderstichele, H.; Eechaute, W.; Lacroix, E.; Leusen, I., 1987: The effects of neonatal androgenization of male rats on testosterone metabolism by the hypothalamus-pituitary-gonadal axis. Male rats were androgenized on the third postnatal day by a single injection of 1 mg testosterone propionate. The in vitro metabolism of [4-14C]testosterone by pituitary and hypothalamus homogenates was investigated at the age of 90 days. The pitu...

Cheung C.Y., 1983: Prolactin suppresses luteinizing hormone secretion and pituitary responsiveness to lhrh by a direct action at the anterior pituitary. In pathological or experimental hyperprolactinemia, the elevated circulating levels of PRL [prolactin] are the usual cause of the impairment in gonadotropic function. It was determined whether PRL could suppress basal LH [luteinizing hormone] secr...