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Effects of yohimbine on plasma levels of leptin in normal and streptozotocin induced diabetic rats






Acta Medica Iranica 44(2): 77-82

Effects of yohimbine on plasma levels of leptin in normal and streptozotocin induced diabetic rats

Leptin affects paraventricular nucleus of hypothalamus and reduces appetite while activation of alpha <sub>2</sub>-adrenoceptors at this site has opposite action. The reducing effect of alpha <sub>2</sub>-adrenoceptors inhibition on body weight and appetite and also enhancing effects on lipolysis, sympathetic activation and plasma insulin levels in animals have been reported.


Accession: 015676027



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