Section 17
Chapter 16,145

Inhibition of the glutamate uptake in the excitatory neuromuscular synapse of the locust by delta-philanthotoxin; a component of the venom of the solitary wasp Philanthus triangulum F. A high resolution autoradiographic study

van Marle, J.; Piek, T.; Lind, A.; van Weeren-Kramer, J.

Comparative Biochemistry and Physiology. C Comparative Pharmacology and Toxicology 79(1): 213-215


ISSN/ISBN: 0742-8413
PMID: 6149870
DOI: 10.1016/0742-8413(84)90187-7
Accession: 016144492

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Glutamate uptake in insect [Schistocerca gregaria] neuromuscular junctions is inhibited by .delta.-philanthotoxin. Two other components of the Philanthus venom (.beta.- and .gamma.-philanthotoxin) do not affect this glutamate uptake. No synergism between the active .delta.-philanthotoxin and the 2 inactive components had to be assumed to explain the inhibition by the Philanthus venom.

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