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RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae



RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae



Journal of Clinical Microbiology 45(7): 2289-2292



Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin.

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Accession: 016833544

Download citation: RISBibTeXText

PMID: 17522276

DOI: 10.1128/jcm.00349-07


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