Whole-body bone mineral content, lean body mass, and fat mass measured by dual-energy X-ray absorptiometry in a population of normal Canadian children and adolescents

Sala, A.; Webber, C.E.; Morrison, J.; Beaumont, L.F.; Barr, R.D.

Canadian Association of Radiologists Journal 58(1): 46-52


ISSN/ISBN: 0846-5371
PMID: 17408162
Accession: 017693279

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Measurements of body composition have evident value in evaluating growing children and adolescents, and dual-energy X-ray absorptiometry (DXA) is a tool that provides accurate measurements of whole-body bone mineral content (WBBMC), lean body mass (LBM), and fat mass (FM). To interpret such measurements in the context of ill health, normative values must be available. Such information could be expected to be regionally specific because of differences in ethnic, dietary, and physical activity determinants. In this study, DXA was performed with Hologic densitometers in normal girls (n=91) and boys (n=88) between 3 and 18 years of age. The derivation of normal ranges is presented for boys and girls. The correlation of the sum of WBBMC, LBM, and FM with directly measured body weight was almost perfect (r>0.997). As expected, FM and body mass index correlated strongly. The normal values for WBBMC, LBM, and FM from this study are compared with other Canadian data and with published normative data from Argentina and the Netherlands, all of which use different densitometers. The results of this study allow the calculation of z scores for each facet of body composition and facilitate the use of DXA to report routine evaluations of body composition in children and adolescents.