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C5A anaphylatoxin and its seven transmembrane-segment receptor

C5A anaphylatoxin and its seven transmembrane-segment receptor

Annual Review of Immunology 12: 775-808

ISSN/ISBN: 0732-0582

PMID: 8011297

DOI: 10.1146/annurev.iy.12.040194.004015

The molecular cloning of the C5a receptor places this molecule in the superfamily of G-protein coupled receptors. This superfamily is characterized by the presence of signature motifs including seven hydrophobic domains which span the cell membrane and impart a predicted serpentine topology to the receptor proteins.

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Accession: 017797489

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