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Effect of butyrate on adenovirus infection in semipermissive cells



Effect of butyrate on adenovirus infection in semipermissive cells



Virology 124(1): 188-191



Adenovirus 2 stimulated cellular DNA synthesis in quiescent cultures of semipermissive tsAF8 cells and 3T3 cells. Such stimulation was inhibited by Na-butyrate, which also inhibited viral DNA replication in tsAF8 cells. In addition, butyrate inhibited the expression of early regions ElA and E2 of adenovirus 2 in both tsAF8 and 3T3 cells, while it had little effect on permissive HeLa cells.

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Accession: 017870896

Download citation: RISBibTeXText

PMID: 6823744

DOI: 10.1016/0042-6822(83)90304-5



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