+ Site Statistics
References:
52,654,530
Abstracts:
29,560,856
PMIDs:
28,072,755
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Intermediate filament proteins: many unanswered questions, few unquestioned answers



Intermediate filament proteins: many unanswered questions, few unquestioned answers



Biochemistry and Cell Biology 70(10-11): 842-848



Major constituents of the cytoskeleton and the nuclear matrix, cytoplasmic intermediate filament subunits and nuclear lamins belong to a multigene family of proteins whose function is poorly understood. It has now become a general contention that important clues to the physiological roles of these proteins may reside in their developmental and tissue-specific expression patterns, as well as their cellular organization. The present review brings into focus experimental strategies that have been developed, over the past few years, to gain insights into the cellular mechanisms regulating the molecular polymorphism and supramolecular assembly of intermediate filaments. In this context new concepts are discussed that may be pivotal for the orientation of future studies on intermediate filament proteins.

(PDF emailed within 0-6 h: $19.90)

Accession: 017969405

Download citation: RISBibTeXText

PMID: 1297350

DOI: 10.1139/o92-132



Related references

AIDS: unanswered questions or unquestioned answers?. Biomedicine & PharmacoTherapy 47(5): 181-182, 1993

Review: amyloidogenesis-unquestioned answers and unanswered questions. Journal of Structural Biology 130(2-3): 99-108, 2000

Influenza 1970: unquestioned answers and unanswered questions. Archives of Environmental Health 21(3): 286-292, 1970

Unquestioned answers or unanswered questions: beliefs about science guide responses to uncertainty in climate change risk communication. Risk Analysis 32(6): 992-1002, 2012

What we do and do not know about women and kidney diseases: Questions unanswered and answers unquestioned : Reflection on World Kidney Day and International Woman's Day. Pediatric Nephrology, 2018

What we know and do not know about women and kidney diseases: questions unanswered and answers unquestioned: reflection on World Kidney Day and International Womens Day. Internal Medicine Journal 48(2): 113-123, 2018

What we know and do not know about women and kidney diseases; Questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Woman's Day. Brazilian Journal of Medical and Biological Research 51(7): E7315-E7315, 2018

What we do and do not know about women and kidney diseases; Questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Woman's Day. Nephrology, 2017

What We Do and Do Not Know About Women and Kidney Diseases; Questions Unanswered and Answers Unquestioned: Reflection on World Kidney Day and International Womans Day. American Journal of Hypertension 31(3): 375-384, 2018

What we know and do not know about women and kidney diseases: questions unanswered and answers unquestioned: reflection on World Kidney Day and International Women's Day. Internal Medicine Journal 48(2): 113-123, 2018

What we do and do not know about women and kidney diseases; questions unanswered and answers unquestioned: Reflection on World Kidney Day and International Women's Day
. Clinical Nephrology, 2018

Influenza 1970:Unquestioned Answer and Unanswered Questions. Archives of Environmental Health An International Journal 21(3): 286-292, 1970

25 years rehabilitation. Questions--answers, unanswered questions--retrospective answers. Die Rehabilitation 31(3): 182-186, 1992

Cytoplasmic intermediate filament proteins of invertebrates are closer to nuclear lamins than are vertebrate intermediate filament proteins; sequence characterization of two muscle proteins of a nematode. Embo Journal 8(11): 3221-3227, 1989

Intermediate filaments: new proteins, some answers, more questions. Current Opinion in Cell Biology 7(1): 46-54, 1995