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RasGRP4, a new mast cell-restricted ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs


RasGRP4, a new mast cell-restricted ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs



The Journal of Biological Chemistry 277(28): 756-74




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Accession: 018082016

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Related references

RasGRP4, a new mast cell-restricted Ras guanine nucleotide-releasing protein with calcium- and diacylglycerol-binding motifs. Identification of defective variants of this signaling protein in asthma, mastocytosis, and mast cell leukemia patients and demonstration of the importance of RasGRP4 in mast cell development and function. Journal of Biological Chemistry 277(28): 25756-25774, 2002

RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs. Science 280(5366): 1082-1086, 1998

The Diacylglycerol-dependent translocation of ras guanine nucleotide-releasing protein 4 inside a human mast cell line results in substantial phenotypic changes, including expression of interleukin 13 receptor alpha2. Journal of Biological Chemistry 283(3): 1610-1621, 2008

Mast cells in airway hyporesponsive C3H/HeJ mice express a unique isoform of the signaling protein Ras guanine nucleotide releasing protein 4 that is unresponsive to diacylglycerol and phorbol esters. Journal of Immunology 171(1): 390-397, 2003

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