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Retinal waves and visual system development

Retinal waves and visual system development

Annual Review of Neuroscience 22: 29-47

ISSN/ISBN: 0147-006X

PMID: 10202531

DOI: 10.1146/annurev.neuro.22.1.29

Many pathways in the developing visual system are restructured and become highly organized even before vision occurs. Yet the developmental processes underlying the remodeling of visual connectivity are crucially dependent on retinal activity. Surprisingly, the immature and light-insensitive retina spontaneously generates a pattern of rhythmic bursting activity during the period when the connectivity patterns of retinal ganglion cells are shaped.

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Accession: 018098355

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